Built in 1321 by Carmelite monks, St. Anne's Church went on play an important role in the history of the Reformation. In 1518 that Martin Luther stayed here with the Carmelite friars when he was in town to meet the papal legate, Cardinal Cajetan, who demanded that Luther submit to the pope. St. Anne's Church converted to Lutheranism in 1545. The Goldsmith's Chapel was added in 1420; the Fugger's Chapel in 1509. The spire was added in 1607 by Elias Holl.
The church was restored and redesigned in the Baroque and Rococo styles between 1747 and 1749.